Dietary Supplements Solutions
low- to midpolarity phase
- General-purpose columns for residual solvents, alcohols, oxygenates, and volatile organic compounds.
- Equivalent to USP G43 phase.
polar phase; Crossbond polyethylene glycol
- Low-bleed PEG column ensures long column lifetimes.
- Temperature range: 40 °C to 260 °C.
- Equivalent to USP G14, G15, G16, G20, and G39 phases.
- USP equivalent standards for the revised USP <467> general chapter—compliance without the cost—compare prices today.
- The only complete source for USP <467>.
- Fast, simple sample extraction and cleanup using dSPE—Fourfold increases in sample throughput.
- Complete offering for AOAC and European Methods.
- Single and multiple component standards as specified in EN Method 15662.
low-polarity phase; Crossbond 1,4-bis(dimethylsiloxy)phenylene dimethyl polysiloxane
- Engineered to be a low-bleed GC-MS column.
- Excellent inertness for active compounds.
- General-purpose columns
—ideal for GC-MS analysis of semivolatiles, polycyclic aromatic compounds, chlorinated hydrocarbons, phthalates, phenols, amines, organochlorine pesticides, organophosphorus pesticides, drugs, solvent impurities, and hydrocarbons.
- Temperature range: -60 °C to 350 °C.
Ligand Type: proprietary polar modified and functionally bonded C18
Particle: 3 µm or 5 µm, spherical
Pore Size: 100 Å
Carbon Load: 15%
Surface Area: 300 m
pH Range: 2.5 to 8
Maximum Temperature: 80 °C
Revised USP 467 Residual Solvent Method - Satisfy New Method Requirements with Restek Columns and Standards
The United States Pharmacopeia recently revised the general chapter on residual solvent analysis, USP <467>, to mirror the International Conference on Harmonization (ICH) guidelines for the identification, control and quantification of residual solvents. This revision, effective July 1, 2007, replaces previous methods that were not consistent with the ICH guidelines. Here we provide an overview, chromatograms, and technical tips for successfully running the new procedure.
Restek has developed the first QuEChERS-based method for determining pesticide residues in dietary supplements. This simple, cost-effective procedure reduces matrix interferences as well as sample prep variation among technicians.
Analysis of pesticide residues in foods is complicated by the large number of target compounds. LC-MS/MS analysis using an Aqueous C18 column provides more comprehensive results than GC alone.
Rapid Characterization of Garlic VolatilesNo Sample Prep Required! - Using Headspace GC/MS and an Rxi®-5ms Capillary Column
Chromatographic methods for garlic and garlic powder are used by the food and dietary supplement industries to monitor product quality. Here we present a headspace gas chromatography mass spectrometry (HS GC/MS) method for garlic flavor and odor components using an Rxi®-5ms column. This method eliminates sample preparation making the bench work simple and fast. The experimental set-up is ideal for both screening analysis and low-level trace analysis.
An Ultra Aqueous C18 column enables you to use the conditions most effective for this analysis: gradient elution in high aqueous mobile phases. The C18 chains will not collapse in the presence of a high water content. Use this chromatographic system to extract data for specific compounds of interest and to manually inspect spectra for phenolic glycosides, esters of phenolic acid, or other compounds.
Determining Pesticides in Dietary Supplements with QuEChERS Extraction, Cartridge SPE, and GCxGC-TOFMS
The novel approach used here combines QuEChERS extraction, cartridge SPE cleanup, and GCxGC-TOFMS analysis, resulting in good recoveries for a wide range of pesticides in dietary supplements. Matrices include dandelion root, sage, and a multi-herb finished product.
Instruction Sheet for QuEChERS Methodology: AOAC Approach.
Instruction Sheet for QuEChERS Methodology: European and Mini-Multiresidue Method.
QuEChERS is a simple, effective approach to sample prep that can be applied to the analysis of pesticides in dietary supplements. Here, we demonstrate a QuEChERS, cSPE, GC-TOFMS procedure that results in good recoveries for a wide range of pesticides in dandelion root.
This 12-page reference includes a of headspace fundamentals, the revised USP <467> method (July, 2008), chromatography for Procedures A, B, and C, and technical tips for optimization. Guidance on fast, effect method development is given.
QuEChERS dSPE methods simplify extract cleanup, reduce material costs, and improve sample throughput. Here we demonstrate the effectiveness of QuEChERS sample cleanup using a multiresidue analysis of pesticides on strawberries.