Antipsychotic Drug Panel on Raptor Biphenyl by LC-MS/MS

	Peaks	tR (min)	Precursor Ion	Product Ion	Product Ion
1.	Desmethylolanzapine	1.27	299.1	256.1	198.0
2.	Olanzapine	1.32	313.2	256.1	198.1
3.	Lamotrigine	1.86	256.0	211.1	145.0
4.	7-Hydroxyquetiapine	1.90	400.3	269.0	208.0
5.	Molindone	1.95	277.2	100.1	70.2
6.	Clozapine	2.25	328.2	271.1	193.1
7.	9-Hydroxyrisperidone	2.26	427.3	207.1	110.2
8.	Haloperidol	2.38	377.2	123.0	95.1
9.	Risperidone	2.39	411.2	191.0	110.1
10.	Quetiapine	2.48	384.2	253.0	221.2
11.	Ziprasidone	2.51	413.2	194.1	130.0
12.	Asenapine	2.52	286.2	165.1	229.1
13.	Promazine	2.53	285.1	86.0	58.0
14.	Loxapine	2.56	328.1	271.1	193.0
15.	Mesoridazine	2.64	387.2	98.2	126.1
16.	Chlorpromazine	2.68	320.1	86.1	58.1
17.	Oxcarbazepine	2.71	253.1	180.0	208.1
18.	Fluphenazine	2.74	438.3	171.1	143.2
19.	Aripiprazole	2.75	448.2	285.0	176.1
20.	Perphenazine	2.75	404.2	171.1	143.2
21.	Trifluoperazine	2.76	408.2	141.2	113.1
22.	Prochlorperazine	2.79	374.1	141.0	113.1
23.	Thiothixene	2.82	444.2	221.2	235.0
24.	Carbamazepine	2.90	237.1	194.1	165.0
25.	Thioridazine	2.90	371.2	126.1	98.1

LC_CF0608

Column	Raptor Biphenyl (cat.# 9309A12)
Dimensions:	100 mm x 2.1 mm ID
Particle Size:	2.7 µm
Guard Column:	Raptor Biphenyl EXP guard column cartridge 5 mm, 2.1 mm ID, 2.7 µm (cat.# 9309A0252)
Temp.:	30 °C
Sample
Diluent:	Water
Conc.:	2.5 ng/mL
Inj. Vol.:	5 µL
Mobile Phase
A:	Water + 0.1% formic acid
B:	Methanol + 0.1% formic acid
	Time (min) Flow (mL/min) %A %B 0.00 0.6 85 15 3.00 0.6 0 100 3.01 0.6 85 15 5.00 0.6 85 15
Detector	MS/MS
Ion Mode:	ESI+
Mode:	Scheduled MRM
Instrument	UHPLC

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