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Chromatography Columns > HPLC & UHPLC Columns

Browse our complete line of HPLC & UHPLC Columns

Raptor HILIC-Si LC Columns (USP L3)

.... This new breed of chromatographic column allows you to more easily achieve peak separation and faster...

Raptor EtG/EtS LC Column

.... This new breed of chromatographic column allows you to more easily achieve peak separation and faster...

Raptor ARC-18 LC Columns (USP L1)

.... This new breed of chromatographic column allows you to more easily achieve peak separation and faster .0) conditions, the sterically protected ARC-18 offers consistent retention, peak shape, and response for charged ... . Sterically protected to endure low-pH mobile phases without sacrificing retention or peak quality...

Raptor Biphenyl LC Columns (USP L11)

.... This new breed of chromatographic column allows you to more easily achieve peak separation and faster at separating compounds that are hard to resolve or that elute early on C18 and other phenyl chemistries...

Raptor FluoroPhenyl LC Columns (USP L43)

.... This new breed of chromatographic column allows you to more easily achieve peak separation and faster reversed-phase and HILIC separations. Ideal for increasing sensitivity and selectivity in LC ... Capable of both reversed-phase and HILIC separations. Ideal for increasing...

Raptor C18 LC Columns (USP L1)

.... This new breed of chromatographic column allows you to more easily achieve peak separation and faster...

USLC Columns—Ultra Selective Liquid Chromatography

Selectivity is the most influential factor affecting peak separation, or resolution. Restek Ultra Selective Liquid Chromatography (USLC) technology i...

USLC Columns Put the Right Tools in Your LC Method Development Toolbox (PDF 1474kB)

... Chromatography Products The most significant influence on chromatographic peak separation, or resolution the impact of column selectivity on peak separation, or resolution, we can see why choosing the right ... column selectivity, peak separation, stationary phase, chromatographic resolution, USLC...

USLC Columns: Choose Columns Fast. Develop Methods Faster. (PDF 1815kB)

... of orthogonal selectivity—the most influential factor affecting peak separation, or resolution—to provide Drives Separations Quickly and effectively resolve analytes by understanding and controlling selectivity ... column selectivity, peak separation, stationary phase, chromatographic resolution...

Get Equivalent GC-MS Results Faster with Restek’s GC Accelerator Kit and EZGC Method Translator (PDF 1618kB)

... that produces narrower peaks, which allow relative peak separations to be maintained and compressed into shorter peak separation, but the peaks elute in a much shorter analysis time. 12PCB 31 & 281234567899.359.8510...

A Rapid and Sensitive LC-MS/MS Method for the Analysis of Three Forms of Thyroid Hormones Using Raptor Biphenyl LC Columns (PDF 486kB)

... column. Note: peak separation is critical for accurate analysis because these compounds have identical L) into the LC-MS/MS for analysis. Results Chromatographic Separation of Thyroid Hormones Since the most...

Dissecting Raptor LC Columns: A closer look at a new species (PDF 1725kB)

... accelerates analysis time, it has little effect on resolution (i.e., peak separation). Selectivity or “core-shell” particles) has been proven to provide fast separations with lower backpressures...

USLC Columns Put the Right Tools in Your LC Method Development Toolbox Understanding Selectivity in Reversed Phase Separations – A Simplified Approach to HPLC and UHPLC Column Selection

...The most significant influence on chromatographic peak separation, or resolution, is column - and time-intensive method development. If we consider the impact of column selectivity on peak separation ... Column selectivity has the most significant influence on chromatographic peak separation...

Guide to GC Column Selection and Optimizing Separations Brochure (PDF 3879kB)

... more plates per meter and sharper peaks, leading to better separation efficiencies. When more complex samples need to be analyzed, smaller ID columns can produce better separation of closely eluting peaks...

USLC Column Selection & Mobile Phase Adjustment Guide (PDF 1682kB)

...) technology is the directed application of selectivity—the most influential factor affecting peak separation range of selectivity in the market, so you can simply and effectively separate almost any combination...

Determining Pesticides in Dietary Supplements with QuEChERS Extraction, Cartridge SPE, and GCxGC-TOFMS (PDF 1695kB)

... phases were cho-sen to maximize peak separation.Instrument conditions are shown in Figure 1.Calibration with Lindane in one-dimensional GC-TOFMS.This GCxGC separation is shown in Figure 5 as the peak immedi...

One Analysis, One Column, Less than 9 Minutes for Over 60 Multiclass Antibiotics (PDF 903kB)

.... [Figure 6]) • Highly efficient peak separation and fast analysis times. • Versatility and global : Conc. Peaks tR (min) (ng/mL) Precursor Ion Product Ion Product Ion 1. Desacetyl cephapirin 0.70 150...

News: Understanding Selectivity in Reversed Phase Separations – A Simplified Approach to HPLC and UHPLC Column Selection

Author(s): Rick Lake, Ty Kahler Published By: Restek Corporation Year of Publication: 2011 Link: http://www.restek.com/Technical-Resources/Technical-Library/Pharmaceutical/general_PHAN1348 Abstract: Column selectivity has the most significant influence on chromatographic peak separation, or resolution, so choosing the right column can greatly speed up HPLC and UHPLC method … Continue reading

Raptor HILIC-Si: Simplify the Switch to HILIC (PDF 2013kB)

... selective USLC technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation. Restek is extending the speed...

Raptor C18 LC Columns Brochure (PDF 2375kB)

... separations and speeding up analysis times with standard HPLC instruments. Raptor then evolved to bring and data quality with high efficiency and peak symmetry, and they are built to exacting specifications...

Raptor SPP Core-Shell LC Columns

Raptor SPP LC columns offer higher efficiency for drastically faster analysis times, better selectivity for substantially improved resolution, increa...

News: New Raptor™ FluoroPhenyl Phase: the Power of HILIC and RP Modes in One LC Column

Restek has now extended the speed and reliability of Raptor™ column technology into the HILIC realm with the addition of Raptor™ FluoroPhenyl columns. Restek’s Raptor™ FluoroPhenyl phase offers chromatographers the ability to run in reversed-phase or HILIC mode for a … Continue reading

News: Simplify the Switch to HILIC with Raptor HILIC-Si Columns

Restek is bringing the speed and reliability of Raptor LC columns into the HILIC realm with the addition of the Raptor HILIC-Si column. HILIC is an increasingly popular alternative to reversed-phase LC for challenging polar analytes because it provides better … Continue reading

Get Equivalent GC-MS Results Faster with Restek’s GC Accelerator Kit and EZGC Method Translator

... that produces narrower peaks, which allow relative peak separations to be maintained and compressed into shorter and translated method. The translated method provides the same elution order and relative peak separation ... it easy to get an equivalent separation in less time. By moving to a shorter column and adopting...

ChromaBLOGraphy: Simple translation of GC methods from helium to hydrogen carrier gas

I had a presentation at PittCon last year discussing using hydrogen and nitrogen carrier gases for the gas chromatography of organochlorine pesticides.  I showed how you can substitute nitrogen at the same linear velocity as hydrogen, while keeping the same oven temperature program used for hydrogen and get a similar chromatogram, albeit with wider peaks […]

News: New Raptor™ ARC-18 Columns Are Born for LC-MS/MS

The birth of Restek’s new Raptor™ SPP LC column line began with the innovative Biphenyl phase, and it has now grown to include a new Restek® phase: the ARC-18. Designed and intended specifically for use on LC-MS/MS systems, the Raptor™ … Continue reading

News: Raptor™ Speed, Efficiency, and Ruggedness is Now Available in C18

Every LC lab has a cache of C18s, but every C18 is not created equal. Because the chemistry tends to be similar, the silica support that carries this ubiquitous octadecylsilane phase becomes vitally important. When you need a general-purpose LC … Continue reading

News: Struggling with EtG/EtS matrix interferences?

A Raptor EtG/EtS column is your solution! Typical methods for EtG and EtS analysis have several limitations: poor resolution from matrix components, long run times that limit sample throughput, and short column lifetimes. Restek has developed a new Raptor EtG/EtS … Continue reading

News: Restek Unleashes Superior Raptor Performance on Your UHPLC Analyses — Now with 1.8 μm Particles

Raptor LC columns have been providing higher efficiencies, faster analyses, and rock-solid reliability to HPLC users for several years. And they have just evolved again. Restek has brought the benefits of Raptor columns to those who have made the leap … Continue reading

News: Experience Selectivity Accelerated With New Raptor™ SPP LC Columns and Guards

Restek is excited to announce the evolution of superficially porous particles with the introduction of Raptor™ LC columns. Superficially porous particles (commonly referred to as SPP or “core-shell” particles) changed the world of LC by dramatically boosting column efficiency and … Continue reading

Benefits and Considerations of Converting to Hydrogen Carrier Gas

... negative impact on efficiency. Peak separations were maintained and since peaks are twice as narrow . Realistically, analysis times can be reduced by a factor of 1.5 or 2 with only minor losses in separation, which...

A Rapid and Sensitive LC-MS/MS Method for the Analysis of Three Forms of Thyroid Hormones Using Raptor Biphenyl LC Columns

...:  Chromatographic separation of T3 and rT3 on the Raptor Biphenyl column. Note: peak separation is critical L) into the LC-MS/MS for analysis. Results Chromatographic Separation of Thyroid Hormones...

Novel Column Chemistry—High Impact, Low Cost Technology

..., creating a versatility needed in method development. The selectivity, or peak separation, of a C18 is often be dovetailed together, not as separate technology choices. Just as UHPLC and mass spectrometry can be coupled...

Restek LC Columns and Accessories (PDF 17555kB)

....e., peak separation). Selectivity, on the other hand, has a substantial impact on resolution, but shows . • Achieve excellent separation of critical isobars with no tailing peaks. • Run fast and reliable high...

ChromaBLOGraphy: [4]Troubleshooting HPLC- Fronting Peaks

Patterns in your HPLC chromatography can exhibit telltale signs that point toward probable sources of error.  In this brief series of posts, we have looked at possible scenarios that you may encounter in the laboratory and how you might approach resolving those difficulties. Any time you have difficulty with poor peak shape, it is also […]

ISC 2018

Here’s a sneak peek at what we’ll be up to during this year’s show.

Determining Pesticides in Dietary Supplements with QuEChERS Extraction, Cartridge SPE, and GCxGC-TOFMS

... (cat.# 20429). These orthogonal phases were chosen to maximize peak separation. Instrument independent separations to a sample in one analysis. GCxGC involves a serial column configuration (differing...

ChromaBLOGraphy: [3]Troubleshooting HPLC- Tailing Peaks

Patterns in your HPLC chromatography can exhibit telltale signs that point toward probable sources of error.  In this brief series of posts, we will look at possible scenarios that you may encounter in the laboratory and how you might approach resolving those difficulties. If you are having difficulty with tailing, it is likely that you […]

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