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Chromatography Columns > HPLC & UHPLC Columns

Browse our complete line of HPLC & UHPLC Columns

Raptor EXP Guard Column Cartridges

... of SPP with the resolution of USLC technology. Learn more at www.restek.com/raptor ...

Raptor HILIC-Si LC Columns (USP L3)

... known as SPP or "core-shell" particles) with the resolution of highly selective USLC technology...

Raptor EtG/EtS LC Column

... known as SPP or "core-shell" particles) with the resolution of highly selective USLC technology...

Raptor Biphenyl LC Columns (USP L11)

... known as SPP or "core-shell" particles) with the resolution of highly selective USLC technology...

Raptor ARC-18 LC Columns (USP L1)

... known as SPP or "core-shell" particles) with the resolution of highly selective USLC technology...

Raptor FluoroPhenyl LC Columns (USP L43)

... known as SPP or "core-shell" particles) with the resolution of highly selective USLC technology...

Raptor C18 LC Columns (USP L1)

... known as SPP or "core-shell" particles) with the resolution of highly selective USLC technology...

USLC Columns—Ultra Selective Liquid Chromatography

Selectivity is the most influential factor affecting peak separation, or resolution. Restek Ultra Selective Liquid Chromatography (USLC) technology is the directed application of orthogonal selectivity to help the practicing chromatographer develop methods more efficiently and mor...

USLC Columns: Choose Columns Fast. Develop Methods Faster. (PDF 1815kB)

...RESTEK USLC Ultra Selective Liquid Chromatography Choose Columns Fast. Develop Methods Faster is Ultra Selective Liquid Chromatography (USLC) technology? This technique is the directed application ... , method development, UHPLC, HPLC, USLC, reversed phase...

USLC Column Selection & Mobile Phase Adjustment Guide (PDF 1682kB)

...RESTEK USLC Ultra Selective Liquid Chromatography Choose Columns Fast. Develop Methods Faster . USLC Column Selection & Mobile Phase Adjustment Guide Ultra Selective Liquid Chromatography (USLC ... reversed phase chromatography, target analyte, mobile phase adjustment, solute retention, USLC...

USLC Columns Put the Right Tools in Your LC Method Development Toolbox (PDF 1474kB)

...General Interest USLC Columns Put the Right Tools in Your LC Method Development Toolbox phases—Restek’s USLC column set—that encompass the widest selectivity range available on the market ... column selectivity, peak separation, stationary phase, chromatographic resolution, USLC...

Infographic: Judging Raptor SPP Core-Shell Particles—2.7 vs. 5 µm Particle Sizes (PDF 3137kB)

... out our technical note on this subject at www.restek.com/raptor TECH TIP: CHOOSE WISELY USLC Superficially Porous w/USLC Technology Faster; Excellent Resolution: Selectivity Accelerated! Superficially...

Dissecting Raptor LC Columns: A closer look at a new species (PDF 1725kB)

... Ultra Selective Liquid Chromatography (USLC) phases to offer chromatographers the best of both worlds . By being the first to combine the speed of SPP with the resolution of highly selective USLC technology...

Increase Data Quality for Sulfonamide Antibiotics Analysis by HPLC and UHPLC (PDF 975kB)

... between UV and MS detection. • Maximize sample throughput by combining USLC selectivity with UHPLC speed peak resolution, we chose a Biphenyl column, part of our USLC family of phases, for this work. Due...

USLC Columns Put the Right Tools in Your LC Method Development Toolbox Understanding Selectivity in Reversed Phase Separations – A Simplified Approach to HPLC and UHPLC Column Selection

...-subtraction model (H-S model), identify a set of just 4 stationary phases—Restek’s USLC column set—that encompasses was calculated relative to a C18 benchmark. The columns showing high Fs values—like the 4 Restek USLC phases ... . In this article, we discuss column choice and identify a set of just 4 stationary phases—Restek’s USLC column ... , "method development", USLC, "reversed phase", UHPLC, HPLC, "H-S Model"...

Raptor SPP Core-Shell LC Columns

Raptor SPP LC columns offer higher efficiency for drastically faster analysis times, better selectivity for substantially improved resolution, increa...

Restek Advantage, 2011.1 (PDF 3826kB)

... Liquid Chromatography? USLC is the directed application of selectiv-ity—the most influential factor of USLC stationaryphase chemistries available.Selectivity Drives SeparationsBy understanding...

Restek Advantage, 2012.1 (PDF 14846kB)

... the Best LC-MS Column/Mobile Phase Combination Using USLC Columns and a Scouting Gradient Liquid Chromatography (USLC) column set represents the widest range of reversed phase selectivity...

News: The New USLC® Toolbox Gives You All the Right Tools—All in One Box

Restek’s USLC® column set represents the widest range of reversed phase selectivity available with just 4 stationary phases: Aqueous C18, IBD, Biphenyl, and PFP Propyl. It simplifies column choice for fast, effective method development—and new USLC® toolboxes make things even … Continue reading

The Effects of LC Particle Choice on Column Performance: Raptor 1.8 µm Superficially Porous Particles (SPP) for UHPLC Analyses (PDF 878kB)

... with the selectivity of USLC technology, so you get the separating power of Restek’s stationary phases combined come to UHPLC with the selectivity of Restek’s USLC phases—in this example, the Raptor Biphenyl 1.8 μm...

LC-MS/MS Analysis of Paraquat and Diquat without Ion-Pairing Reagents (PDF 530kB)

... of SPP with the resolution of USLC technology. Learn more at www.restek.com/raptor Hybrid Ferrule U...

Trace-Level Analysis of Melamine and Related Compounds by LC-MS/MS (PDF 763kB)

... of SPP with the resolution of USLC technology. Learn more at www.restek.com/raptor Hybrid Ferrule U...

LC-MS/MS Analysis of Urinary Free Cortisol and Cortisone without Matrix Interferences (PDF 515kB)

...) or 400 bar/5,800 psi (5 μm). Raptor SPP LC columns combine the speed of SPP with the resolution of USLC...

Fast, Accurate LC-MS/MS Method for Folate Deficiency Biomarkers in Plasma (PDF 513kB)

...). Raptor SPP LC columns combine the speed of SPP with the resolution of USLC technology. Learn more at www...

Highly Selective LC-MS/MS Analysis of Mycotoxins from Multiple Classes (PDF 556kB)

... the speed of SPP with the resolution of USLC technology. Learn more at www.restek.com/raptor Hybrid...

High-Throughput Analysis of Cannabinoids by LC-UV (PDF 1054kB)

... bar/5,800 psi (5 μm). Raptor SPP LC columns combine the speed of SPP with the resolution of USLC...

Comprehensive LC-MS/MS Analysis of 15 Bisphenols in 8 Minutes (PDF 519kB)

.../04/scopingdocument- on-bisphenols.pdf USLC Column Interaction Profile Biphenyl Dispersion H...

Raptor SPP C18 Columns Sales Sheet (PDF 1888kB)

... Technologies, Inc. Raptor SPP LC columns combine the speed of SPP with the resolution of USLC technology...

Raptor ARC-18 LC Columns Sales Sheet (PDF 1872kB)

... LC columns combine the speed of SPP with the resolution of USLC technology. Learn more at www...

Raptor ARC-18 LC Columns Brochure (PDF 4942kB)

... particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC ,000 psi. Raptor SPP LC columns combine the speed of SPP with the resolution of USLC technology. Learn...

Raptor FluoroPhenyl LC Columns Brochure (PDF 3042kB)

... selective USLC technology, improving separations and speeding up analysis times with standard HPLC is 830 bar/12,000 psi. Raptor SPP LC columns combine the speed of SPP with the resolution of USLC...

Raptor FluoroPhenyl LC Columns Sales Sheet (PDF 1816kB)

... columns combine the speed of SPP with the resolution of USLC technology. Learn more at www...

LC-MS/MS Analysis of 58 Antipsychotics and Antidepressants in Human Urine (PDF 792kB)

... detection. Raptor Biphenyl LC Columns (USP L11) USLC Column Interaction Profile Biphenyl Dispersion H...

Raptor Biphenyl LC Columns Sales Sheet (PDF 3731kB)

... the speed of SPP with the resolution of USLC technology. Learn more at www.restek.com/raptor Hybrid Ferrule...

Raptor HILIC-Si: Simplify the Switch to HILIC (PDF 2013kB)

... selective USLC technology. This new breed of chromatographic column allows you to more easily achieve peak combine the speed of SPP with the resolution of USLC technology. Learn more at www...

Raptor C18 LC Columns Brochure (PDF 2375kB)

... as SPP or “core-shell” particles) with the resolution of highly selective USLC technology, improving the speed of SPP with the resolution of USLC technology. Learn more at www.restek.com/raptor Description...

Raptor Biphenyl LC Columns Brochure (PDF 6071kB)

... selective USLC technology, improving separations and speeding up analysis times with standard HPLC LC columns combine the speed of SPP with the resolution of USLC technology. Learn more at www...

Increase Data Quality for Sulfonamide Residue Analysis by HPLC and UHPLC Using Unique Biphenyl Column Selectivity

... sample throughput by combining USLC selectivity with UHPLC speed. The analysis factor affecting peak resolution, we chose a Biphenyl column, part of our USLC family of phases...

Restek LC Columns and Accessories (PDF 17409kB)

....1 6 www.restek.com/LC Selectivity Accelerated The speed of SPP with the resolution of USLC porous particles with Restek’s unique Ultra Selective Liquid Chromatography (USLC) phases to offer...

Method Evaluation: Analysis of Phosphatidylethanol (PEth) in Human Whole Blood by LC-MS/MS (PDF 874kB)

... increased retention of hydrophilic compounds. CH3 Si CH3 O F F F F F USLC Column Interaction Profile...

Analysis of Synthetic Cannabinoids and Metabolites: Adding New Compounds to an Existing LC-MS/MS Method (PDF 870kB)

... of superficially porous particles (SPP) with the resolution of highly selective USLC technology, we chose it when...

Restek Essentials: Featured Chromatography Products 2018.1 (PDF 5439kB)

... of SPP with the resolution of USLC technology. Learn more at www.restek.com/raptor EXP Direct Connect...

News: Understanding Selectivity in Reversed Phase Separations – A Simplified Approach to HPLC and UHPLC Column Selection

Author(s): Rick Lake, Ty Kahler Published By: Restek Corporation Year of Publication: 2011 Link: http://www.restek.com/Technical-Resources/Technical-Library/Pharmaceutical/general_PHAN1348 Abstract: Column selectivity has the most significant influence on chromatographic peak separation, or resolution, so choosing the right column can greatly speed up HPLC and UHPLC method … Continue reading

The Restek Biphenyl: Leading Resolution in LC since 2005

With ten years of unrivaled performance, Restek's time-tested Biphenyl has been proven to be the ideal LC column for clinical diagnostic, pain, pharm...

The Effects of LC Particle Choice on Column Performance: Raptor 1.8 µm Superficially Porous Particles (SPP) for UHPLC Analyses

... results. Raptor LC columns represent the fusion of SPP speed with the selectivity of USLC technology, so with the selectivity of Restek’s USLC phases—in this example, the Raptor Biphenyl 1.8 µm column resolves fifteen...

ChromaBLOGraphy: Restek at Separation Science meeting, Kuala Lumpur, Malaysia

Separation science was organized the 4th time in Kuala Lumpur Malaisia. The 2 days conference offered a practical program on developments in GC and LC with a lot of time to discuss applications while enjoying some of the local cuisine. Restek participated with a booth where displaying consumable products for GC, LC, and sample preparation(fig [...]

News: Experience Selectivity Accelerated With New Raptor™ SPP LC Columns and Guards

Restek is excited to announce the evolution of superficially porous particles with the introduction of Raptor™ LC columns. Superficially porous particles (commonly referred to as SPP or “core-shell” particles) changed the world of LC by dramatically boosting column efficiency and … Continue reading

Diagnosing and Preventing High Back Pressure Problems in LC Systems (PDF 5850kB)

... with the resolution of USLC technology. Learn more at www.restek.com/raptor EXP Guard Cartridges Unidirectional...

News: New Raptor™ FluoroPhenyl Phase: the Power of HILIC and RP Modes in One LC Column

Restek has now extended the speed and reliability of Raptor™ column technology into the HILIC realm with the addition of Raptor™ FluoroPhenyl columns. Restek’s Raptor™ FluoroPhenyl phase offers chromatographers the ability to run in reversed-phase or HILIC mode for a … Continue reading

News: Simplify the Switch to HILIC with Raptor HILIC-Si Columns

Restek is bringing the speed and reliability of Raptor LC columns into the HILIC realm with the addition of the Raptor HILIC-Si column. HILIC is an increasingly popular alternative to reversed-phase LC for challenging polar analytes because it provides better … Continue reading

ChromaBLOGraphy: Restek made big impression at Analytica, Germany

Analytica, one of the biggest analytical exhibition that is organized every second year in Munich, Germany, looks back on another highly successful meeting. Compared with Pittcon US, the differences are huge in nr. of exhibitors, the quality if the exhibits and especially, the number of people that participate. Especially if taken in account this exhibit [...]

ChromaBLOGraphy: Which LC Phase Do I Need?

So you’re thinking about doing HPLC (or UHPLC) and don’t have a method? You’ve never even seen a method for anything remotely similar. You might have even searched our HPLC chromatogram database for the application and haven’t found anything.  (After all, that’s the quickest and easiest way to get some ideas.) What to do… Let’s [...]

ChromaBLOGraphy: Restek at Arab lab 2012

From march 26-29  Arab lab exposition  was organized in Dubai. The show attracted many international visitors from countries in middle east and was a great platform to discuss analytical challenges. Restek was showing their solutions on GC and LC and products were displayed as part of the Shimadzu booth, see picture1. Besides petroleum related innovations, [...]

News: New Raptor™ ARC-18 Columns Are Born for LC-MS/MS

The birth of Restek’s new Raptor™ SPP LC column line began with the innovative Biphenyl phase, and it has now grown to include a new Restek® phase: the ARC-18. Designed and intended specifically for use on LC-MS/MS systems, the Raptor™ … Continue reading

News: Raptor™ Speed, Efficiency, and Ruggedness is Now Available in C18

Every LC lab has a cache of C18s, but every C18 is not created equal. Because the chemistry tends to be similar, the silica support that carries this ubiquitous octadecylsilane phase becomes vitally important. When you need a general-purpose LC … Continue reading

News: Struggling with EtG/EtS matrix interferences?

A Raptor EtG/EtS column is your solution! Typical methods for EtG and EtS analysis have several limitations: poor resolution from matrix components, long run times that limit sample throughput, and short column lifetimes. Restek has developed a new Raptor EtG/EtS … Continue reading

News: Restek Unleashes Superior Raptor Performance on Your UHPLC Analyses — Now with 1.8 μm Particles

Raptor LC columns have been providing higher efficiencies, faster analyses, and rock-solid reliability to HPLC users for several years. And they have just evolved again. Restek has brought the benefits of Raptor columns to those who have made the leap … Continue reading

Growing Analytical Solutions for Cannabis Testing: Innovative Products and Expertise for Fast, Accurate, Reliable Results (PDF 8494kB)

... of optimized USLC phase chemistry. These columns are ideal for cannabis testing because they quickly separate...

News: Separation Science 2012 Features Jaap de Zeeuw as Key Invited Speaker

We are proud to announce that Restek’s own Jaap de Zeeuw was invited to speak at Separation Science 2012 in Kuala Lumpur, Malaysia. Jaap joined chromatography experts from around the globe in presenting his work (see below for the abstract) … Continue reading

News: Restek Bolsters its Product Expertise With Two New Hires

Restek recently expanded its marketing department by bringing on two new Product Marketing Managers: Paul Connolly (LC Columns) and Scott Adams (GC Accessories). Paul and Scott will manage day-to-day operations and product maintenance while former PMMs Rick Lake and Kelli … Continue reading

ChromaBLOGraphy: Join the Restek CAC and Separate Triphenylene and Chrysene and other PAHs, and Many Other Compounds

Restek just founded the Coalition Against Coelution (CAC) based around their highly selective stationary phases for GC and LC.  If you stroll around on the website and the blog, you’ll find the CAC manifesto in action, whether it is the Rtx-Dioxin2 GC column, with its TCDD and TCDF specificity; the Rtx-CLPesticides GC columns, which are [...]

Analysis of Synthetic Cannabinoids and Metabolites: Adding New Compounds to an Existing LC-MS/MS Method

... USLC technology, we chose it when developing a simple dilute-and-shoot method that included both...

ChromaBLOGraphy: Fluorophenyl LC Phases- what you should know

They may be called PFP, PFPP, pentafluorophenyl, fluorophenyl or F5 phases. What they all have in common is the structure shown above (the pentafluorophenyl  group) attached to the silica particles. Most modern phases contain a propyl spacer between the above group and the silica, so that the phase looks something like this:     A […]

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